HCLSIG/PharmaOntology/Meetings/2009-04-16 Conference Call

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Conference Details

  • Date of Call: Thursday April 16, 2009
  • Time of Call: 12:00pm Eastern Daylight Time (EDT), 17:00 British Summer Time (BST)
  • Dial-In #: +1.617.761.6200 (Cambridge, MA)
  • Dial-In #: +33.4.89.06.34.99 (Nice, France)
  • Dial-In #: +44.117.370.6152 (Bristol, UK)
  • Participant Access Code: 42572 ("HCLS2").
  • IRC Channel: irc.w3.org port 6665 channel #HCLS2 (see W3C IRC page for details, or see Web IRC)
  • Duration: ~1h
  • Convener: Susie

Agenda

Minutes

Attendees: Matthias, Colin, Holger, Sandor, Lynn, Bosse, Christi, Elgar, Susie

Apologies: Larisa

Topic: Action Items

Susie: http://esw.w3.org/topic/HCLSIG/PharmaOntology/Actions

Susie: Sandor, your action item was to look at three new roles - what progress?

sszalma: clinical team lead & medical team lead we have been discussing.

Susie: we had hoped to have finalized the roles by last time - we have to get it done by the f2f

susie: trish was going to review possible ontologies; had done some previously

susie: susie & christi to distribute icbo abstract; done

susie: i will find out from helen about sk2

susie: john was going to propose some classes and properties; done

Topic: Questions finalized...

susie: http://esw.w3.org/topic/HCLSIG/PharmaOntology/Roles

christi: mol&cell biol - how do we pull in the chemistry?

colin: I'll paste in the chemistry things from above

lynn: i'll edit the wiki page

colin: is there polypharmacology/off-target effects

christi: moving on to in vitro biologist...

lynn: for cell lines you should look at ATCC but it's not an ontology

christi: on to in vivo biology...

lynn: do we have obi?

christi: we need interspecies comparisons

lynn/colin: model organism databases

lynn: also entrez genes

colin: what about online mendelian inheritance in animals? sszalma: paolo romano (in italy) has done a cell line dictionary

sszalma http://nar.oxfordjournals.org/cgi/content/full/37/suppl_1/D925

matthias_samwald: an indian group has done a similar thing

sszalma that is the right reference

matthias_samwald: it's an owl ontology

colin: what is "vehicle"

christi: it's how the active ingredient is conveyed

christi: moving on to "clinical trial formulator"

lynn: there's a human phenotype ontology, and DO

bosse: who is the clinical trial formulator? someone within the pharma company? responsible for the study design? has md?

christi: yes

bosse: this is v similar in my mind to a lead physician: looks at scientific content of study

susie: can we rename the role with a slash to make it clear that it's more than one role?

bosse: "clinical trial formulator/lead physician view"

christi: do the questions seem comprehensive?

susie: yes

christi: moving on to "Clinical Decision Support System Implementer View" - making sense of the data

lynn: what's epoc?

susie: clinical trial ontology from stanford

lynn: copied long line of ontologies from question before

holger_stenzhorn: advanced clinical genomic trials (http://www.ifomis.org/acgt)

christi: questions look pretty comprehensive

christi: okay, statisticians

colin: obi probably best for statistics

lynn: pato for phenotypes

colin: sequence ontology for genotypes

susie: i could ask someone i know for more questions here

christi: marketing...

susie: we should merge these into the strategic view above?

susie: we also need sales

christi: do we have any ontologies?

colin: no

susie: what media should we use for advertising?

susie: is our advertising in compliance with regulatory authorities?

colin: and local laws

colin: rename to "Sales and Marketing view"

christi: Primary Care Clinician View colin: infectious disease ontology (ido)

lynn: core ido most relevant

christi: non-drug treatments? homoeopathic?

colin: lifestyle changes like stopping smoking/exercise

susie: also interferences with, for example, grapefruit

christi: add those ontologies to specialty medical provider

christi: moving on to specialty medical provider...

christi: moving on to health plan provider...

susie: would be good to be build it out a bit - helen from agfa and vipul kashyap (will be at f2f) may be able to help

lynn: what are the data sources on what is allowable?

colin: looking at http://www.nice.org.uk/

susie: at the f2f, let's ensure these people add stuff to the wiki.

susie: vipul mentioned the Health plan Model

christi: bye everyone. thanks for all of your input!

Topic: F2F

lynn: i'll be out of the country for the f2f

susie: f2f is 30/4 and 1/5

http://esw.w3.org/topic/HCLSIG/Meetings/2009-04-30_F2F

susie: if you're dialling in could you add your name to that page and say you're dialling in

susie: moving on to the f2f... a breakout session of 3 h: (1) poster (2) key entities (3) brainstorming around use cases

colin: when are breakout sessions?

susie: 1330 to 1630 EST

lynn: will there be a report?

susie: there will be task breakout reports - should be pretty self-describing

Topic: Proposed Classes

http://esw.w3.org/topic/HCLSIG/PharmaOntology/Ontology

susie: john madden has proposed some classes and properties

susie: identified on the basis of word count frequency - we will be discussing those at the f2f

susie: also think about what use cases we're interested in building out

holger_stenzhorn: how are we prioritizing this?

susie: focus on the roles

Topic: ICBO Poster

susie: we managed to submit a proposal for a poster for ICBO

susie: thank you everyone who contributed - holger and elgar have contributed already and it would be useful to discuss this at the f2f

susie: someone at the group will be there

colin: i will

susie: are you willing to stand in front of the poster?

colin: yes

holger_stenzhorn: who is putting this on paper? i am willing to help?

susie: thank you for all your contributions - we're filling a gap lots of people are interested in having filled